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P-LLY Cautionary Statement Regarding Forward-Looking Statements This press release contains forward-looking statements (as that term is defined in the Private Securities Litigation Reform Act of 1995) about retatrutide as a potential treatment for adults with obesity or overweight and at least one weight-related comorbidity, potential efficacy and tolerability of retatrutide, and the timeline for future readouts, presentations, and other milestones relating to retatrutide and its clinical trials and reflects Lilly's current beliefs and expectations

Orfoglipron, a once-daily oral molecule, remains in successful late-stage development

Moreover, alterations in the gut microbiota as described in mice require careful analysis in human studies including the assessment of a possible growth advantage for pathogenic bacteria as part of a commensal microbiome or with respect to systemic effects and clinical relevance